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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PKN3 All Species: 19.09
Human Site: S866 Identified Species: 30
UniProt: Q6P5Z2 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6P5Z2 NP_037487.2 889 99421 S866 L T P P A P H S L L T A R Q Q
Chimpanzee Pan troglodytes XP_001159776 886 99121 S863 L T P P A P H S L L T A R Q Q
Rhesus Macaque Macaca mulatta XP_001110500 1011 111864 S988 L T P P A P H S L L T A R Q Q
Dog Lupus familis XP_548434 951 104664 S928 L T P P D P R S P L T A R Q Q
Cat Felis silvestris
Mouse Mus musculus Q8K045 878 97863 S855 L T P P V S Q S S L T A R Q Q
Rat Rattus norvegicus O08874 985 112050 F951 V S N F D D E F T S E A P I L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506565 993 109767 C970 L T P P N P R C P L T P R Q Q
Chicken Gallus gallus XP_422357 1013 114806 T987 T S E A P I L T P P R E P R I
Frog Xenopus laevis Q7ZX15 486 56292 L464 P P D R Y D N L D A L E S D Q
Zebra Danio Brachydanio rerio XP_697542 940 106140 P916 R L K P V L T P P Q T P F F L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13678 634 71138 I612 G N E V V R C I N Q D E F A G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34885 707 80133 A685 V L T P S D P A V V R A I N Q
Sea Urchin Strong. purpuratus XP_787090 799 90414 P774 A E H P V L T P A K D P R E L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P24583 1151 131500 S1129 P T L T P L P S V L T T S Q Q
Red Bread Mold Neurospora crassa P87253 1142 127954 P1119 S V T P V L T P V Q S V L S Q
Conservation
Percent
Protein Identity: 100 97.7 81.5 84.2 N.A. 83.2 49.9 N.A. 64.2 48.9 26.2 52.2 N.A. 28 N.A. 29.1 41.5
Protein Similarity: 100 97.8 82.9 87.6 N.A. 88.4 63.6 N.A. 72.9 63 36.6 67.6 N.A. 41.5 N.A. 43.9 58.2
P-Site Identity: 100 100 100 80 N.A. 73.3 6.6 N.A. 66.6 0 6.6 13.3 N.A. 0 N.A. 20 13.3
P-Site Similarity: 100 100 100 80 N.A. 73.3 20 N.A. 66.6 20 13.3 13.3 N.A. 0 N.A. 53.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.2 27.1
Protein Similarity: N.A. N.A. N.A. N.A. 41.7 43.2
P-Site Identity: N.A. N.A. N.A. N.A. 40 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 7 20 0 0 7 7 7 0 47 0 7 0 % A
% Cys: 0 0 0 0 0 0 7 7 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 14 20 0 0 7 0 14 0 0 7 0 % D
% Glu: 0 7 14 0 0 0 7 0 0 0 7 20 0 7 0 % E
% Phe: 0 0 0 7 0 0 0 7 0 0 0 0 14 7 0 % F
% Gly: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % G
% His: 0 0 7 0 0 0 20 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 7 0 7 0 0 0 0 7 7 7 % I
% Lys: 0 0 7 0 0 0 0 0 0 7 0 0 0 0 0 % K
% Leu: 40 14 7 0 0 27 7 7 20 47 7 0 7 0 20 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 7 0 7 0 7 0 7 0 0 0 0 7 0 % N
% Pro: 14 7 40 67 14 34 14 20 27 7 0 20 14 0 0 % P
% Gln: 0 0 0 0 0 0 7 0 0 20 0 0 0 47 67 % Q
% Arg: 7 0 0 7 0 7 14 0 0 0 14 0 47 7 0 % R
% Ser: 7 14 0 0 7 7 0 40 7 7 7 0 14 7 0 % S
% Thr: 7 47 14 7 0 0 20 7 7 0 54 7 0 0 0 % T
% Val: 14 7 0 7 34 0 0 0 20 7 0 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _